Graphical abstract unavailableBook chapter
Integrated Microwave Assisted Synthesis and Solid-Supported Reagents
Microwave-Assisted Organic Synthesis · 2005 · Chapter 6 · 133–174
Abstract not currently available.
Research record
Publications
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201 publications found
Graphical abstract unavailable
Graphical abstract unavailableJournal article
Microwave-Enhanced Palladium-Catalysed Reactions
Innovations in Pharmaceutical Technology · 2005 · 18 · 86–90
Microencapsulated palladium has been shown to be compatible with microwave heating, offering benefits such as increased yields, higher purities and simple work-up procedures, and permitting access to many previously unattainable molecular assemblies.
Graphical abstract unavailableJournal article
Non-Metal Catalysed Intramolecular Alkyne Cyclotrimerization Reactions Promoted by Focussed Microwave Heating in Batch and Flow Modes.
Org. Biomol. Chem. · 2005 · 3 · 3365–3368
A number of oligomeric alkynes underwent [2 + 2 + 2] intramolecular trimerization to afford arenes under metal-free conditions using focussed microwave heating.
Graphical abstract unavailableJournal article
Synthesis of Alkaloid Natural Products using Supported Reagents and Scavengers
Curr. Org. Chem. · 2005 · 9 · 1521–1534
Supported reagents and scavengers have become key tools for the synthesis of biologically important molecular entities. The complexity of the target molecules attainable and the synthetic flexibility afforded by these systems now rivals any solution phase app…
Graphical abstract unavailableJournal article
Synthesis of the Alkaloid Natural Products (+)-Plicane and (–)-Obliquine using Polymer-Supported Reagents and Scavengers
Ind. & Eng. Chem. Res. · 2005 · 44 · 8588–8592
Two new naturally occurring amaryllidaceae alkaloids have been synthesized, using a divergent approach facilitated by the use of polymer-supported reagents and scavengers.
Graphical abstract unavailableJournal article
The Rapid Preparation of 5-Substituted-2-Aminosulfonamide-1,3,4-oxadiazoles Using Polymer-Supported Reagents and Scavengers
Tetrahedron · 2005 · 61 · 5323–5349
Herein, we report on the preparation of a library of 5-substituted-2-amino-1,3,4-oxadiazoles and the corresponding thiadiazole analogues. Presented is a one-pot preparation of the 2-aminosulfonylated analogues through a three component coupling of an acylhydr…
Graphical abstract unavailableJournal article
Microwave assisted Leimgruber-Batcho reaction for the preparation of indoles, azaindoles and pyrroylquinolines.
Org. Biomol. Chem. · 2004 · 2 · 160–167
The development of enhanced conditions for Lewis acid catalysed Leimgruber–Batcho indole synthesis using microwave acceleration is described.
Graphical abstract unavailableJournal article
Multi-step application of immobilized reagents and scavengers: A total synthesis of epothilone C.
Chem. Euro. J. · 2004 · 10 · 2529–2547
The total synthesis of the cytotoxic antitumour natural product epothilone C has provided a stage for the exploitation and further development of immobilized reagent methods. A stereoselective convergent synthetic strategy was applied, incorporating polymer-…
Graphical abstract unavailableBook chapter
Development of New Synthetic Tools for the Preparation of Biologically Active Molecules
Chemical Probes in Biology (NATO Science series) · 2003 · Series Volume 129 · 235–244
The synthesis of organic compounds, especially biologically active molecules, is a very complex task involving many important decision making steps. These decisions are especially important at the synthesis planning stage where issues of regio-, chemo- and st…
Graphical abstract unavailableJournal article
Enantioselective synthesis of the tetrahydrobenzylisoquinoline alkaloid (-)-norarmepavine using polymer supported reagents.
Heterocyles · 2003 · 60 · 2707–2715
We describe, in full, the enantioselective synthesis of the tetrahydrobenzylisoquinoline alkaloid (-)-norarmepavine (1) in 77% e.e. This compound was prepared using solid-supported reagents and scavengers in multi-step sequences of reactions to give materials…
Graphical abstract unavailableBook chapter
Polymer Supported Hydroxide
Electronic Encylopaedia of Reagents for Organic Synthesis · 2003 · Electronic · E1–E2
Abstract not currently available.
Graphical abstract unavailableBook chapter
Supported Reagents and Scavengers in Multi-Step Organic Synthesis
Polymeric Materials in Organic Synthesis and Catalysis · 2003 · Chapter 2 · 53–136
Abstract not currently available.