Capabilities

Start with the scientific problem

The group’s capabilities connect molecular and route design, process development, reaction engineering, flow chemistry, automation and analytics. Technology is selected around the chemistry and the decision that the work must support.

Problem-led explorer

What problem are you trying to address?

12 capabilities shown

Capability directory

Scientific and technical capabilities

DesignProcessEngineeringAutomation

Design

Established expertise

Retrosynthetic route design

Compare plausible synthetic routes using chemical feasibility, step economy, safety, supply, waste and translation constraints.

Design

Established expertise

Organic and heterocyclic synthesis

Develop practical routes to heterocyclic, functional and medicinally relevant molecular architectures.

Process

Established expertise

Reaction optimisation and profiling

Identify the variables controlling conversion, selectivity, robustness and impurity formation.

Process

Established expertise

Telescoping and sequence integration

Connect reaction and work-up operations to reduce handling, isolations, time and material losses.

Engineering

Established expertise

Batch-to-flow translation

Assess whether continuous processing resolves a genuine limitation in mixing, heat transfer, residence time, pressure or inventory.

Engineering

Established expertise

Gas–liquid and multiphase processing

Control interfacial contact, gas delivery and reaction inventory for challenging multiphase transformations.

Engineering

Established expertise

On-demand reactive-intermediate generation

Generate unstable, toxic or energetic intermediates in controlled quantities and consume them without creating significant standing inventory.

Engineering

Future redevelopment interest

Photochemical processing

Use controlled irradiation, short optical paths and residence-time definition to investigate photochemical transformations.

Engineering

Collaboration opportunity

Bespoke reactor and apparatus development

Design apparatus around the transport, containment, sampling or processing needs of a defined chemical problem.

Automation

Established expertise

Automated sampling

Collect timed or condition-dependent samples consistently while reducing repetitive manual intervention.

Automation

Future redevelopment interest

Inline and online analysis

Connect appropriate analytical measurements to experiments so that chemistry and process behaviour can be assessed in context.

Automation

Seeking collaboration

Automated experimental orchestration

Coordinate experiments, process conditions, sampling and data capture around a clearly defined scientific decision.

Route to delivery

Capabilities work as a connected system

A project may draw on several capabilities, but each addition must have a clear purpose.

01

Define the molecular objective

Clarify the target, route constraints and evidence required.

02

Understand the chemistry

Establish mechanism, selectivity, kinetics, hazards and impurities.

03

Select the process environment

Choose batch, flow, light, pressure, automation or a combined workflow based on need.

04

Build transferable evidence

Produce robust conditions, analytical understanding and a credible path to delivery.

Capability status

Historic evidence does not automatically imply current availability

Each capability is classified as established expertise, future redevelopment interest or a collaboration opportunity. Practical availability is confirmed only after the scientific scope, facilities, people and funding route are understood.

See the future programme

Discuss a project

Describe the problem, not a preferred technology

Useful initial enquiries explain the chemistry, present limitation, desired outcome, available evidence and likely collaboration or funding route.

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