Research

Chemistry, process and technology considered as one system

The Baxendale Group works from molecular strategy through process understanding to the technology required for safe, efficient and scalable execution. Flow and automation are tools within that scientific approach, not ends in themselves.

01

Design the route

Define the molecular objective, compare retrosynthetic options and choose chemistry with a credible path forward.

02

Understand the process

Establish kinetics, selectivity, hazards, impurities and a robust operating window.

03

Engineer the execution

Select flow, automation, analytics or bespoke equipment where a clear scientific advantage exists.

Four connected pillars

Research expertise

Each area has a distinct technical focus while contributing to the same route-to-process objective.

01

Synthetic and heterocyclic chemistry

Designing the underlying chemistry, not simply changing the equipment in which it runs.

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02

Route design and process chemistry

From a plausible transformation to a safe, selective and transferable synthetic route.

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03

Flow chemistry and reaction engineering

Engineering the reaction environment around the needs of the chemistry.

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04

Automation and analytics

Turning experiments into connected, information-rich process-development workflows.

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Programme clarity

Record, direction and opportunity are kept distinct

Established expertise

Demonstrated through previous research, publications, equipment development and collaboration.

Future direction

A scientifically grounded area intended for the next programme, but not represented as currently funded activity.

Seeking partners or funding

An area where a credible collaborator, candidate or funding route could enable substantive work.

Future programme

Rebuilding around scientific value

The next phase will be developed through strong projects, external funding, academic and industrial partnerships and researchers with appropriate support.

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Collaboration

Bring a real chemical or process problem

Discussions are welcomed where synthetic insight, process development or enabling technology can make a material difference.

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