Baxendale GroupAdvanced synthetic chemistry, engineered for scaleDepartment of Chemistry

Research record

Publications

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Synthetic and heterocyclic chemistryRoute design and process chemistryFlow chemistry and reaction engineeringAutomation and analyticsPhotochemistryHazardous and reactive intermediatesImmobilised reagents and scavengers

14 publications found for Automation and analytics

Cover of Org. Lett.
Graphical abstract for Fully Automated Continuous Flow Synthesis of 4,5-Disubstituted Oxazoles

Journal article

Fully Automated Continuous Flow Synthesis of 4,5-Disubstituted Oxazoles

Baumann, M.; Baxendale, I. R.; Ley, S. V.; Smith, C. D.; Tranmer, G. K.

Org. Lett. · 2006 · 8 · 5231–5234

Synthetic and heterocyclic chemistryFlow chemistry and reaction engineeringAutomation and analyticsImmobilised reagents and scavengers

A multipurpose mesofluidic flow reactor capable of producing gram quantities of material has been developed as an automated synthesis platform for the rapid on-demand synthesis of key building blocks and small exploratory libraries. The reactor is configured …

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Cover of Synlett
Graphical abstract for Preparation of the Neolignan Natural Product Grossamide by a Continuous Flow Process.

Journal article

Preparation of the Neolignan Natural Product Grossamide by a Continuous Flow Process.

Baxendale, I. R.; Griffiths-Jones, C. M.; Ley, S. V.; Saaby, S.; Tranmer, G. K.

Synlett · 2006 · (3) · 427–430

Synthetic and heterocyclic chemistryFlow chemistry and reaction engineeringAutomation and analytics

This article describes the first enantioselective total synthesis of 2-aryl-2,3-dihydro-3-benzofurancarboxyamide neolignan, grossamide (1) using a fully automated and scalable flow reactor.

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